HS-PEG11-CH2CH2N3

Modify Date: 2024-01-15 23:12:30

HS-PEG11-CH2CH2N3 Structure
HS-PEG11-CH2CH2N3 structure
Common Name HS-PEG11-CH2CH2N3
CAS Number 2148986-08-5 Molecular Weight 587.72
Density N/A Boiling Point N/A
Molecular Formula C24H49N3O11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS-PEG11-CH2CH2N3


HS-PEG11-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name HS-PEG11-CH2CH2N3

 HS-PEG11-CH2CH2N3 Biological Activity

Description HS-PEG11-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C24H49N3O11S
Molecular Weight 587.72

 Safety Information

Hazard Codes Xi