2148986-06-3

2148986-06-3 structure

2148986-06-3 structure

Name: HS-PEG7-CH2CH2N3
Chemical Name: HS-PEG7-CH2CH2N3
CAS Number: 2148986-06-3
Molecular Formula: C₁₆H₃₃N₃O₇S
Molecular Weight: 411.51
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:44:41
Modify Date: 2024-01-04 18:46:58
HS-PEG7-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HS-PEG7-CH2CH2N3

Description	HS-PEG7-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₆H₃₃N₃O₇S
Molecular Weight	411.51

Hazard Codes	Xi