Azidoethyl-PEG2-t-Butyl ester

Modify Date: 2024-01-08 12:32:53

Azidoethyl-PEG2-t-Butyl ester Structure
Azidoethyl-PEG2-t-Butyl ester structure
Common Name Azidoethyl-PEG2-t-Butyl ester
CAS Number 2144777-83-1 Molecular Weight 351.49
Density N/A Boiling Point N/A
Molecular Formula C13H25N3O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azidoethyl-PEG2-t-Butyl ester


Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azidoethyl-SS-PEG2-Boc

 Azidoethyl-PEG2-t-Butyl ester Biological Activity

Description Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H25N3O4S2
Molecular Weight 351.49
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