(2-pyridyldithio)-PEG2-t-butyl ester

Modify Date: 2024-02-02 23:17:05

(2-pyridyldithio)-PEG2-t-butyl ester Structure
(2-pyridyldithio)-PEG2-t-butyl ester structure
Common Name (2-pyridyldithio)-PEG2-t-butyl ester
CAS Number 2144777-73-9 Molecular Weight 359.50
Density N/A Boiling Point N/A
Molecular Formula C16H25NO4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2-pyridyldithio)-PEG2-t-butyl ester


(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (2-Pyridyldithio)-PEG2-Boc

 (2-pyridyldithio)-PEG2-t-butyl ester Biological Activity

Description (2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H25NO4S2
Molecular Weight 359.50