1398044-50-2
1398044-50-2 structure
- Name: Thiol-PEG2-t-butyl ester
- Chemical Name: Thio-PEG2-t-butyl ester
- CAS Number: 1398044-50-2
- Molecular Formula: C11H22O4S
- Molecular Weight: 250.355
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-14 20:32:49
- Modify Date: 2024-01-10 18:07:34
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Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Thio-PEG2-t-butyl ester |
|---|---|
| Synonyms |
Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-, 1,1-dimethylethyl ester
MFCD22574781 2-Methyl-2-propanyl 3-[2-(2-sulfanylethoxy)ethoxy]propanoate |
| Description | Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 330.6±27.0 °C at 760 mmHg |
| Molecular Formula | C11H22O4S |
| Molecular Weight | 250.355 |
| Flash Point | 200.0±11.6 °C |
| Exact Mass | 250.123886 |
| LogP | 1.75 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.462 |