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2144777-73-9

2144777-73-9 structure
2144777-73-9 structure
  • Name: (2-pyridyldithio)-PEG2-t-butyl ester
  • Chemical Name: (2-Pyridyldithio)-PEG2-Boc
  • CAS Number: 2144777-73-9
  • Molecular Formula: C16H25NO4S2
  • Molecular Weight: 359.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:54:38
  • Modify Date: 2024-02-02 23:17:05
  • (2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (2-Pyridyldithio)-PEG2-Boc
Description (2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H25NO4S2
Molecular Weight 359.50