VU 6010572
Modify Date: 2024-02-17 17:25:18
VU 6010572 structure
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Common Name | VU 6010572 | ||
|---|---|---|---|---|
| CAS Number | 2126784-39-0 | Molecular Weight | 339.366 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H18FNO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VU 6010572A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM; show no inhibition for mGlu2 (IC50>30 uM); displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.). |
| Name | VU 6010572 |
|---|
| Description | A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM; show no inhibition for mGlu2 (IC50>30 uM); displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.). |
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| References | References 1. Engers JL, et al. ACS Med Chem Lett. 2017 Aug 15;8(9):925-930. View Related Products by Target mGluR |
| Molecular Formula | C20H18FNO3 |
|---|---|
| Molecular Weight | 339.366 |