JAK1-IN-4
Modify Date: 2024-01-10 09:49:37
JAK1-IN-4 structure
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Common Name | JAK1-IN-4 | ||
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| CAS Number | 2091134-35-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JAK1-IN-4JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1]. |
| Name | AZD4205 |
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| Description | JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1]. |
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| Related Catalog | |
| Target |
JAK1:85 nM (IC50) JAK2:12.8 μM (IC50) |
| References |
[1]. Annika Birgitta Margareta ÅSTRAND, et al. Compounds and methods for inhibiting jak. |
| No Any Chemical & Physical Properties |