MARK-IN-4

Modify Date: 2025-08-24 19:07:59

MARK-IN-4 Structure
MARK-IN-4 structure
Common Name MARK-IN-4
CAS Number 1990492-86-8 Molecular Weight 421.52
Density N/A Boiling Point N/A
Molecular Formula C21H23N7OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MARK-IN-4


MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1].

 Names

Name MARK-IN-4

 MARK-IN-4 Biological Activity

Description MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1].
Related Catalog
References

[1]. Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016;26(17):4362-4366.

 Chemical & Physical Properties

Molecular Formula C21H23N7OS
Molecular Weight 421.52

 Safety Information

Hazard Codes Xi
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