PKC-IN-6c

Modify Date: 2024-02-07 17:01:53

PKC-IN-6c Structure
PKC-IN-6c structure
Common Name PKC-IN-6c
CAS Number 2026603-86-9 Molecular Weight 565.762
Density N/A Boiling Point N/A
Molecular Formula C35H43N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKC-IN-6c


A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM); effectively blocks amphetamine-induced locomotor stimulation, more potently inhibits PKC than tamoxifen and reduces amphetamine-stimulated dopamine efflux.

 Names

Name PKC-IN-6c

 PKC-IN-6c Biological Activity

Description A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM); effectively blocks amphetamine-induced locomotor stimulation, more potently inhibits PKC than tamoxifen and reduces amphetamine-stimulated dopamine efflux.
References References 1. Newman AH, et al. Neuropsychopharmacology. 2017 Jun 8. doi: 10.1038/npp.2017.116. View Related Products by Target PKC

 Chemical & Physical Properties

Molecular Formula C35H43N5O2
Molecular Weight 565.762
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