860468-10-6
860468-10-6 structure
- Name: PKC-IN-7
- Chemical Name: PKC-IN-7
- CAS Number: 860468-10-6
- Molecular Formula: C26H22ClN3O2
- Molecular Weight: 443.931
- Create Date: 2020-01-20 16:57:56
- Modify Date: 2024-02-24 17:22:07
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PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
| Name | PKC-IN-7 |
|---|
| Description | PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM. |
|---|---|
| References | References 1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786. View Related Products by Target PKC |
| Molecular Formula | C26H22ClN3O2 |
|---|---|
| Molecular Weight | 443.931 |