2026603-86-9
2026603-86-9 structure
- Name: PKC-IN-6c
- Chemical Name: PKC-IN-6c
- CAS Number: 2026603-86-9
- Molecular Formula: C35H43N5O2
- Molecular Weight: 565.762
- Create Date: 2020-01-11 20:57:16
- Modify Date: 2025-10-23 02:42:08
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A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM); effectively blocks amphetamine-induced locomotor stimulation, more potently inhibits PKC than tamoxifen and reduces amphetamine-stimulated dopamine efflux.
| Name | PKC-IN-6c |
|---|
| Description | A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM); effectively blocks amphetamine-induced locomotor stimulation, more potently inhibits PKC than tamoxifen and reduces amphetamine-stimulated dopamine efflux. |
|---|---|
| References | References 1. Newman AH, et al. Neuropsychopharmacology. 2017 Jun 8. doi: 10.1038/npp.2017.116. View Related Products by Target PKC |
| Molecular Formula | C35H43N5O2 |
|---|---|
| Molecular Weight | 565.762 |