Name | PKC-IN-6c |
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Description | A novel, potent, brain permeant PKC inhibitor with IC50 of 80 nM, without detectable binding to the estrogen receptor (Ki>10 uM); effectively blocks amphetamine-induced locomotor stimulation, more potently inhibits PKC than tamoxifen and reduces amphetamine-stimulated dopamine efflux. |
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References | References 1. Newman AH, et al. Neuropsychopharmacology. 2017 Jun 8. doi: 10.1038/npp.2017.116. View Related Products by Target PKC |
Molecular Formula | C35H43N5O2 |
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Molecular Weight | 565.762 |