Tri-GalNAc-NHS ester

Modify Date: 2024-01-26 11:51:19

Tri-GalNAc-NHS ester Structure
Tri-GalNAc-NHS ester structure
Common Name Tri-GalNAc-NHS ester
CAS Number 1953146-83-2 Molecular Weight 1832.98
Density N/A Boiling Point N/A
Molecular Formula C79H137N11O37 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tri-GalNAc-NHS ester


Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC[1].

 Names

Name Tri-GalNAc-NHS ester

 Tri-GalNAc-NHS ester Biological Activity

Description Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC[1].
Related Catalog
References

[1]. Zhou Y, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.  

 Chemical & Physical Properties

Molecular Formula C79H137N11O37
Molecular Weight 1832.98
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