Tri-GalNAc(OAc)3

Modify Date: 2024-01-31 11:28:31

Tri-GalNAc(OAc)3 Structure
Tri-GalNAc(OAc)3 structure
 Common Name Tri-GalNAc(OAc)3
CAS Number 1159408-64-6 Molecular Weight 1793.91
Density N/A Boiling Point N/A
Molecular Formula C79H128N10O36 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tri-GalNAc(OAc)3


Tri-GalNAc(OAc)3 is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1].

 Names

Name Tri-GalNAc(OAc)3

 Tri-GalNAc(OAc)3 Biological Activity

Description Tri-GalNAc(OAc)3 is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1].
Related Catalog
Target

LYTAC[1]

References

[1]. Ahn G, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17(9):937-946.

 Chemical & Physical Properties

Molecular Formula C79H128N10O36
Molecular Weight 1793.91
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