Tri-GalNAc(OAc)3

Names

[ CAS No. ]:
1159408-64-6

[ Name ]:
Tri-GalNAc(OAc)3

Biological Activity

[Description]:

Tri-GalNAc(OAc)3 is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

LYTAC[1]


[References]

[1]. Ahn G, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17(9):937-946.

Chemical & Physical Properties

[ Molecular Formula ]:
C79H128N10O36

[ Molecular Weight ]:
1793.91

Related Compounds