tri-GalNAc-COOH

Modify Date: 2025-08-25 21:24:40

tri-GalNAc-COOH Structure
tri-GalNAc-COOH structure
Common Name tri-GalNAc-COOH
CAS Number 1953146-81-0 Molecular Weight 1735.91
Density N/A Boiling Point N/A
Molecular Formula C75H134N10O35 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of tri-GalNAc-COOH


tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].

 Names

Name tri-GalNAc-COOH

 tri-GalNAc-COOH Biological Activity

Description tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].
Related Catalog
In Vitro tri-GalNAc-COOH is a biotin-free ASGPR ligand, which failes to deliver NA-650 to HepG2, Huh7, or A549 cells[1].
References

[1]. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.

 Chemical & Physical Properties

Molecular Formula C75H134N10O35
Molecular Weight 1735.91
InChIKey SPYOMGAJOYWUJU-JNYSMVCCSA-N
SMILES CC(=O)NC1C(OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(C)=O)NC(=O)CCOCCOCCOCCOCCOCCC(=O)O)OC(CO)C(O)C1O
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