tri-GalNAc-COOH

Names

[ CAS No. ]:
1953146-81-0

[ Name ]:
tri-GalNAc-COOH

Biological Activity

[Description]:

tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

tri-GalNAc-COOH is a biotin-free ASGPR ligand, which failes to deliver NA-650 to HepG2, Huh7, or A549 cells[1].

[References]

[1]. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₅H₁₃₄N₁₀O₃₅

[ Molecular Weight ]:
1735.91

Related Compounds

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