Tri-GalNAc-NHS ester

Names

[ CAS No. ]:
1953146-83-2

[ Name ]:
Tri-GalNAc-NHS ester

Biological Activity

[Description]:

Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Zhou Y, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₉H₁₃₇N₁₁O₃₇

[ Molecular Weight ]:
1832.98

Related Compounds

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