SBI-553

Modify Date: 2025-08-25 18:46:51

SBI-553 Structure
SBI-553 structure
Common Name SBI-553
CAS Number 1849603-72-0 Molecular Weight 450.55
Density N/A Boiling Point N/A
Molecular Formula C26H31FN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SBI-553


SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM[1].

 Names

Name SBI-553

 SBI-553 Biological Activity

Description SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM[1].
Related Catalog
Target

EC50: 0.34 μM (NTR1)[1].

References

[1]. Pinkerton AB, et al. Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. J Med Chem. 2019 Aug 20.

 Chemical & Physical Properties

Molecular Formula C26H31FN4O2
Molecular Weight 450.55
Storage condition -20°C
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