2073059-82-0
2073059-82-0 structure
- Name: SBI-993
- Chemical Name: SBI-993
- CAS Number: 2073059-82-0
- Molecular Formula: C23H24N4O4S
- Molecular Weight: 452.529
- Catalog: Research Areas Metabolic Disease
- Create Date: 2020-01-20 18:19:56
- Modify Date: 2023-02-03 23:01:08
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SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability; reduces Txnip and Arrdc4 expression to a degree similar to that seen with SBI-477 in human myotubes; reduces muscle and liver TAG levels, enhances insulin signaling, and improved glucose tolerance in mice fed a high-fat diet.
| Name | SBI-993 |
|---|
| Description | SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability; reduces Txnip and Arrdc4 expression to a degree similar to that seen with SBI-477 in human myotubes; reduces muscle and liver TAG levels, enhances insulin signaling, and improved glucose tolerance in mice fed a high-fat diet. |
|---|---|
| References | References 1. Ahn B, et al. J Clin Invest. 2016 Sep 1;126(9):3567-79. View Related Products by Target Other Targets |
| Molecular Formula | C23H24N4O4S |
|---|---|
| Molecular Weight | 452.529 |