1849603-72-0

1849603-72-0 structure

Name: SBI-553
Chemical Name: SBI-553
CAS Number: 1849603-72-0
Molecular Formula: C₂₆H₃₁FN₄O₂
Molecular Weight: 450.55
Catalog: Signaling Pathways GPCR/G Protein Neurotensin Receptor
Create Date: 2019-10-08 12:02:52
Modify Date: 2024-01-14 10:34:57
SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM[1].

Name	SBI-553

Description	SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neurotensin Receptor Research Areas >> Others
Target	EC50: 0.34 μM (NTR1)[1].
References	[1]. Pinkerton AB, et al. Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. J Med Chem. 2019 Aug 20.