t-Butoxycarbonyl-PEG4-NHS ester

Modify Date: 2024-01-17 18:30:23

t-Butoxycarbonyl-PEG4-NHS ester Structure
t-Butoxycarbonyl-PEG4-NHS ester structure
Common Name t-Butoxycarbonyl-PEG4-NHS ester
CAS Number 1835759-75-5 Molecular Weight 447.48
Density N/A Boiling Point N/A
Molecular Formula C20H33NO10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Butoxycarbonyl-PEG4-NHS ester


Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-PEG4-C2-NHS ester
Synonym More Synonyms

 t-Butoxycarbonyl-PEG4-NHS ester Biological Activity

Description Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H33NO10
Molecular Weight 447.48

 Synonyms

MFCD29052203