859230-20-9
859230-20-9 structure
- Name: Boc-NH-PEG4-NHS ester
- Chemical Name: 2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
- CAS Number: 859230-20-9
- Molecular Formula: C20H34N2O10
- Molecular Weight: 462.491
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-06 23:13:45
- Modify Date: 2024-01-08 19:30:05
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Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate |
|---|---|
| Synonyms |
2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, 1,1-dimethylethyl ester |
| Description | Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H34N2O10 |
| Molecular Weight | 462.491 |
| Exact Mass | 462.221344 |
| LogP | -1.66 |
| Index of Refraction | 1.501 |