Boc-NH-PEG4-NHS ester
Modify Date: 2025-08-23 10:18:23
Boc-NH-PEG4-NHS ester structure
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Common Name | Boc-NH-PEG4-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 859230-20-9 | Molecular Weight | 462.491 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H34N2O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Boc-NH-PEG4-NHS esterBoc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H34N2O10 |
| Molecular Weight | 462.491 |
| Exact Mass | 462.221344 |
| LogP | -1.66 |
| Index of Refraction | 1.501 |
| InChIKey | HHPGGUMKDXTEDQ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O |
| 2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate |
| Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, 1,1-dimethylethyl ester |