Mal-amido-PEG4-NHS ester

Modify Date: 2025-08-25 17:45:23

Mal-amido-PEG4-NHS ester structure	Common Name	Mal-amido-PEG4-NHS ester
	CAS Number	756525-99-2	Molecular Weight	513.49500
	Density	1.36±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₁N₃O₁₁	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Mal-amido-PEG4-NHS ester

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonym	More Synonyms

Description	Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Mal-amido-PEG4-NHS ester MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

monodisperse Mal-PEG4-NHS-ester

AmbotzPEG1575

Maleimide-PEG4-NHS Ester

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Price: ￥4784/100 mg