DBCO-NHCO-PEG4-NHS ester

Modify Date: 2024-01-15 16:26:48

DBCO-NHCO-PEG4-NHS ester Structure
DBCO-NHCO-PEG4-NHS ester structure
Common Name DBCO-NHCO-PEG4-NHS ester
CAS Number 2100306-58-7 Molecular Weight 649.69
Density N/A Boiling Point N/A
Molecular Formula C34H39N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-NHCO-PEG4-NHS ester


DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name DBCO-NHCO-PEG4-NHS ester

 DBCO-NHCO-PEG4-NHS ester Biological Activity

Description DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Thornlow DN, et al. Dual Site-Specific Antibody Conjugates for Sequential and Orthogonal Cargo Release. Bioconjug Chem. 2019 Jun 19;30(6):1702-1710.

 Chemical & Physical Properties

Molecular Formula C34H39N3O10
Molecular Weight 649.69

 Safety Information

Hazard Codes Xi