1353016-71-3
1353016-71-3 structure
- Name: DBCO-NHS ester
- Chemical Name: Dibenzocyclooctyne-N-hydroxysuccinimidyl ester
- CAS Number: 1353016-71-3
- Molecular Formula: C23H18N2O5
- Molecular Weight: 402.39900
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-12-03 19:19:27
- Modify Date: 2024-01-12 09:24:05
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DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | Dibenzocyclooctyne-N-hydroxysuccinimidyl ester |
|---|---|
| Synonyms |
DBCO-NHS ester
Dibenzylcyclooctyne-NHS ester Dibenzocyclooctyne-N-hydroxysuccinimidyl ester DBCO-succinyl N-hydroxysuccinimidyl ester 2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate 2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate |
| Description | DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.43±0.1 g/cm3 |
|---|---|
| Boiling Point | 670.2±65.0 °C at 760 mmHg |
| Molecular Formula | C23H18N2O5 |
| Molecular Weight | 402.39900 |
| Exact Mass | 402.12200 |
| PSA | 83.99000 |
| LogP | 2.32330 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
|---|