THP-SS-PEG1-Boc

Modify Date: 2024-02-02 09:29:32

THP-SS-PEG1-Boc Structure
THP-SS-PEG1-Boc structure
Common Name THP-SS-PEG1-Boc
CAS Number 1807503-88-3 Molecular Weight 366.536
Density 1.1±0.1 g/cm3 Boiling Point 470.0±45.0 °C at 760 mmHg
Molecular Formula C16H30O5S2 Melting Point N/A
MSDS N/A Flash Point 222.7±16.7 °C

 Use of THP-SS-PEG1-Boc


THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name THP-SS-PEG1-t-butyl ester
Synonym More Synonyms

 THP-SS-PEG1-Boc Biological Activity

Description THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 470.0±45.0 °C at 760 mmHg
Molecular Formula C16H30O5S2
Molecular Weight 366.536
Flash Point 222.7±16.7 °C
Exact Mass 366.153473
LogP 3.70
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.512

 Synonyms

2-Methyl-2-propanyl 3-(2-{[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethoxy)propanoate
Propanoic acid, 3-[2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
MFCD28505560