THP-PEG1-alcohol structure
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Common Name | THP-PEG1-alcohol | ||
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CAS Number | 2162-31-4 | Molecular Weight | 146.184 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 255.3±30.0 °C at 760 mmHg | |
Molecular Formula | C7H14O3 | Melting Point | 95ºC 22 mm Hg(lit.) | |
MSDS | N/A | Flash Point | 108.2±24.6 °C |
Use of THP-PEG1-alcoholTHP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | Tetrahydropyranylethyleneglycol |
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Synonym | More Synonyms |
Description | THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 255.3±30.0 °C at 760 mmHg |
Melting Point | 95ºC 22 mm Hg(lit.) |
Molecular Formula | C7H14O3 |
Molecular Weight | 146.184 |
Flash Point | 108.2±24.6 °C |
Exact Mass | 146.094299 |
PSA | 38.69000 |
LogP | -0.38 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.460 |
Safety Phrases | 23-24/25 |
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WGK Germany | 3 |
HS Code | 2932999099 |
~90% THP-PEG1-alcohol CAS#:2162-31-4 |
Literature: Eshghi, Hossein; Shafieyoon, Parvaneh Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 10 p. 2149 - 2152 |
~85% THP-PEG1-alcohol CAS#:2162-31-4 |
Literature: Gopinath, Pushparathinam; Nilaya, Surapaneni; Muraleedharan, Kannoth Manheri Organic Letters, 2011 , vol. 13, # 8 p. 1932 - 1935 |
~92% THP-PEG1-alcohol CAS#:2162-31-4 |
Literature: Synthetic Communications, , vol. 36, # 18 p. 2705 - 2710 |
~95%
Detail
|
Literature: Journal of Organic Chemistry, , vol. 63, # 23 p. 8183 - 8187 |
~% THP-PEG1-alcohol CAS#:2162-31-4 |
Literature: Canadian Journal of Chemistry, , vol. 65, p. 213 - 223 |
~% THP-PEG1-alcohol CAS#:2162-31-4 |
Literature: Canadian Journal of Chemistry, , vol. 65, p. 213 - 223 |
HS Code | 2932999099 |
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Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
2-(Tetrahydro-2H-pyran-2-yloxy)ethanol |
Ethanol, 2-[(tetrahydro-2H-pyran-2-yl)oxy]- |
2-(oxan-2-yloxy)ethanol |