3539-40-0
3539-40-0 structure
- Name: THP-CH3-ethyl propionate
- Chemical Name: ethyl 2-(oxan-2-yloxy)propanoate
- CAS Number: 3539-40-0
- Molecular Formula: C10H18O4
- Molecular Weight: 202.24800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-10-01 04:21:30
- Modify Date: 2025-08-26 18:15:04
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THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | ethyl 2-(oxan-2-yloxy)propanoate |
|---|---|
| Synonyms | Tetrahydropyranylethyllactat |
| Description | THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.05g/cm3 |
|---|---|
| Boiling Point | 292.7ºC at 760mmHg |
| Molecular Formula | C10H18O4 |
| Molecular Weight | 202.24800 |
| Flash Point | 125.6ºC |
| Exact Mass | 202.12100 |
| PSA | 44.76000 |
| LogP | 1.48120 |
| Index of Refraction | 1.448 |
|
~%
3539-40-0 |
| Literature: Daiichi Pharmaceutical Co., Ltd. Patent: US5136059 A1, 1992 ; |
| Precursor 3 | |
|---|---|
| DownStream 1 | |
