THP-SS-PEG1-Tos

Modify Date: 2025-08-22 10:27:07

THP-SS-PEG1-Tos Structure
THP-SS-PEG1-Tos structure
Common Name THP-SS-PEG1-Tos
CAS Number 1807512-37-3 Molecular Weight 392.554
Density 1.3±0.1 g/cm3 Boiling Point 539.4±50.0 °C at 760 mmHg
Molecular Formula C16H24O5S3 Melting Point N/A
MSDS N/A Flash Point 280.0±30.1 °C

 Use of THP-SS-PEG1-Tos


THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name THP-SS-PEG1-Tos
Synonym More Synonyms

 THP-SS-PEG1-Tos Biological Activity

Description THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 539.4±50.0 °C at 760 mmHg
Molecular Formula C16H24O5S3
Molecular Weight 392.554
Flash Point 280.0±30.1 °C
Exact Mass 392.078583
LogP 3.58
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.586
InChIKey WJDBLPWPLQRBJB-UHFFFAOYSA-N
SMILES Cc1ccc(S(=O)(=O)OCCSSCCOC2CCCCO2)cc1

 Synonyms

Ethanol, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]-, 4-methylbenzenesulfonate
2-{[2-(Tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethyl 4-methylbenzenesulfonate
MFCD28950768
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