Propargyl-PEG1-SS-PEG1-acid

Modify Date: 2025-08-25 14:29:38

Propargyl-PEG1-SS-PEG1-acid Structure
Propargyl-PEG1-SS-PEG1-acid structure
Common Name Propargyl-PEG1-SS-PEG1-acid
CAS Number 1807503-85-0 Molecular Weight 264.362
Density 1.2±0.1 g/cm3 Boiling Point 428.8±45.0 °C at 760 mmHg
Molecular Formula C10H16O4S2 Melting Point N/A
MSDS N/A Flash Point 213.1±28.7 °C

 Use of Propargyl-PEG1-SS-PEG1-acid


Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Propargyl-PEG1-SS-PEG1-acid
Synonym More Synonyms

 Propargyl-PEG1-SS-PEG1-acid Biological Activity

Description Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 428.8±45.0 °C at 760 mmHg
Molecular Formula C10H16O4S2
Molecular Weight 264.362
Flash Point 213.1±28.7 °C
Exact Mass 264.049011
LogP 2.15
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.545
InChIKey OEMFYMUYWYWVRT-UHFFFAOYSA-N
SMILES C#CCOCCSSCCOCCC(=O)O

 Synonyms

3-(2-{[2-(2-Propyn-1-yloxy)ethyl]disulfanyl}ethoxy)propanoic acid
Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-
MFCD28505557
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