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1807518-78-0

1807518-78-0 structure
1807518-78-0 structure
  • Name: Propargyl-PEG1-SS-PEG1-C2-Boc
  • Chemical Name: Propargyl-PEG1-SS-PEG1-t-butyl ester
  • CAS Number: 1807518-78-0
  • Molecular Formula: C14H24O4S2
  • Molecular Weight: 320.468
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-07-14 02:44:34
  • Modify Date: 2024-01-09 13:29:55
  • Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name Propargyl-PEG1-SS-PEG1-t-butyl ester
Synonyms 2-Methyl-2-propanyl 3-(2-{[2-(2-propyn-1-yloxy)ethyl]disulfanyl}ethoxy)propanoate
MFCD28505559
Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
Description Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Barrientos AG, et al. Gold glyconanoparticles: synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies. Chemistry. 2003 May 9;9(9):1909-21.

Density 1.1±0.1 g/cm3
Boiling Point 407.4±40.0 °C at 760 mmHg
Molecular Formula C14H24O4S2
Molecular Weight 320.468
Flash Point 187.0±15.4 °C
Exact Mass 320.111603
LogP 3.84
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.510
Hazard Codes Xi