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1807503-88-3

1807503-88-3 structure
1807503-88-3 structure
  • Name: THP-SS-PEG1-Boc
  • Chemical Name: THP-SS-PEG1-t-butyl ester
  • CAS Number: 1807503-88-3
  • Molecular Formula: C16H30O5S2
  • Molecular Weight: 366.536
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-11 16:49:53
  • Modify Date: 2024-02-02 09:29:32
  • THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name THP-SS-PEG1-t-butyl ester
Synonyms 2-Methyl-2-propanyl 3-(2-{[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethoxy)propanoate
Propanoic acid, 3-[2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
MFCD28505560
Description THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.1±0.1 g/cm3
Boiling Point 470.0±45.0 °C at 760 mmHg
Molecular Formula C16H30O5S2
Molecular Weight 366.536
Flash Point 222.7±16.7 °C
Exact Mass 366.153473
LogP 3.70
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.512