1807503-88-3

1807503-88-3 structure

Name: THP-SS-PEG1-Boc
Chemical Name: THP-SS-PEG1-t-butyl ester
CAS Number: 1807503-88-3
Molecular Formula: C₁₆H₃₀O₅S₂
Molecular Weight: 366.536
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-11 16:49:53
Modify Date: 2025-09-26 14:25:55
THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	THP-SS-PEG1-t-butyl ester
Synonyms	2-Methyl-2-propanyl 3-(2-{[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]disulfanyl}ethoxy)propanoate Propanoic acid, 3-[2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester MFCD28505560

Description	THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.