DHODH-IN-9
Modify Date: 2025-08-25 12:54:30
DHODH-IN-9 structure
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Common Name | DHODH-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 1644156-41-1 | Molecular Weight | 366.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H23FN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DHODH-IN-9DHODH-IN-9 (Compound 10k) is an azine-bearing analogue and is a human dihydroorotate dehydrogenase inhibitor. DHODH-IN-9 has antiviral effect with a pMIC50 of 7.4[1]. |
| Name | DHODH-IN-9 |
|---|
| Description | DHODH-IN-9 (Compound 10k) is an azine-bearing analogue and is a human dihydroorotate dehydrogenase inhibitor. DHODH-IN-9 has antiviral effect with a pMIC50 of 7.4[1]. |
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| Related Catalog | |
| Target |
pMIC50: 7.4 (DHODH)[1] |
| In Vitro | DHODH-IN-9 (Compound 10k) is a corresponding pyridazine homologue from 3-chloro-6-cyclopropylpyridazine. With few variations, the pattern of antiviral effect for analogues featuring a 5-cyclopylpyridine is somehow mirroring the one seen for the 5-ethylpyrimidyl bearing homologues. DHODH-IN-9 (Compound 10k) is a good antiviral of this group of analogue[1]. |
| References |
| Molecular Formula | C21H23FN4O |
|---|---|
| Molecular Weight | 366.43 |
| InChIKey | HNZNVWVVPQVTKE-UHFFFAOYSA-N |
| SMILES | Cc1c(Cc2ccccc2F)c(OC(C)C)nn1-c1ncc(C2CC2)cn1 |