133676-47-8

133676-47-8 structure

Name: hDHODH-IN-9
Chemical Name: hDHODH-IN-9
CAS Number: 133676-47-8
Molecular Formula: C₂₁H₂₁NO₄
Molecular Weight: 351.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease Lactate Dehydrogenase
Create Date: 2022-07-01 11:38:07
Modify Date: 2024-01-09 18:42:58
hDHODH-IN-9 (Compound 3k) is a potent inhibitor of hDHODH with an IC50 of 0.34 μM. hDHODH-IN-9 demonstrates high cytotoxic activity against MCF-7 and A375 cells and good selectivity. hDHODH-IN-9 has the potential for the research of cancer diseases[1].

Name	hDHODH-IN-9

Description	hDHODH-IN-9 (Compound 3k) is a potent inhibitor of hDHODH with an IC50 of 0.34 μM. hDHODH-IN-9 demonstrates high cytotoxic activity against MCF-7 and A375 cells and good selectivity. hDHODH-IN-9 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
References	[1]. Petrović MM, et al. Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies. Bioorg Chem. 2020;105:104373.

Molecular Formula	C₂₁H₂₁NO₄
Molecular Weight	351.40