GR 103691
Modify Date: 2025-08-27 10:49:21
GR 103691 structure
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Common Name | GR 103691 | ||
|---|---|---|---|---|
| CAS Number | 162408-66-4 | Molecular Weight | 485.617 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 688.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C30H35N3O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 370.3±31.5 °C | |
Use of GR 103691GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites[1]. |
| Name | 4-(4-acetylphenyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites[1]. |
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| Related Catalog | |
| Target |
Ki: 0.4 nM (Human dopamine D3 receptor)[1] |
| In Vitro | GR 103691 shows marked affinity for serotonin1A (5-HT1A) receptors (Ki of 5.8 nM) and α-1 adrenoceptors (Ki of 12.6 nM)[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 688.7±55.0 °C at 760 mmHg |
| Molecular Formula | C30H35N3O3 |
| Molecular Weight | 485.617 |
| Flash Point | 370.3±31.5 °C |
| Exact Mass | 485.267853 |
| PSA | 61.88000 |
| LogP | 4.47 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.582 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| 4'-Acetyl-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}biphenyl-4-carboxamide |
| 4'-Acetyl-N-{4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl}-4-biphenylcarboxamide |
| Tocris-1109 |
| [1,1'-Biphenyl]-4-carboxamide, 4'-acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- |
| MFCD00936840 |