Ginkgolide A

Modify Date: 2024-01-01 23:47:14

Ginkgolide A Structure
Ginkgolide A structure
Common Name Ginkgolide A
CAS Number 15291-75-5 Molecular Weight 408.399
Density 1.6±0.1 g/cm3 Boiling Point 710.1±60.0 °C at 760 mmHg
Molecular Formula C20H24O9 Melting Point 280°C (dec.)
MSDS USA Flash Point 256.5±26.4 °C

 Use of Ginkgolide A


Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.Target: GABA ReceptorGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. Ginkgolide A significantly shortened the sleeping time induced by anesthetics in mice [1]. Ginkgolide A failed to affect apoptotic damage neither in serum-deprived nor in staurosporine-treated neurons [2].

 Names

Name Ginkgolide A
Synonym More Synonyms

 Ginkgolide A Biological Activity

Description Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.Target: GABA ReceptorGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. Ginkgolide A significantly shortened the sleeping time induced by anesthetics in mice [1]. Ginkgolide A failed to affect apoptotic damage neither in serum-deprived nor in staurosporine-treated neurons [2].
Related Catalog
References

[1]. Wada, K., et al., Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics. Biol Pharm Bull, 1993. 16(2): p. 210-2.

[2]. Ahlemeyer, B. and J. Krieglstein, Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry, 2003. 36(S 1): p. 8-14.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 710.1±60.0 °C at 760 mmHg
Melting Point 280°C (dec.)
Molecular Formula C20H24O9
Molecular Weight 408.399
Flash Point 256.5±26.4 °C
Exact Mass 408.142029
PSA 128.59000
LogP -0.13
Vapour Pressure 0.0±5.1 mmHg at 25°C
Index of Refraction 1.631
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206
Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

~%

Ginkgolide A Structure

Ginkgolide A

CAS#:15291-75-5

Literature: Tetrahedron Letters, , vol. 29, # 26 p. 3205 - 3206

 Synonyms

Ginkgolid A
(1R,3R,7S,8S,10R,11S,13S,16S,17R)-8-tert-Butyl-6,17-dihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione
6H-9,4a-(Epoxymethano)-3aH,9H-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1H)-trione, 11-(1,1-dimethylethyl)hexahydro-1,4b-dihydroxy-5-methyl-, (3aR,4aR,4bR,5S,7aS,8aS,9R,11S,11aS)-
BN 5202
GINKGOLIDE A,GINKGO BILOBA L
PRIMULIC ACID 1
gingkolide A
ginkolide A
GINKGOBILOBAP.E.
1,7-DIDEOXYGINKGOLIDE C
ginkgolide a from ginkgo biloba leaves
MFCD07437829
GINKGOLIDE A FROM GINKGO LEAVES
GinkgolideA
(1R,3R,7S,8S,10R,11S,13S,16S,17R)-6,17-Dihydroxy-16-methyl-8-(2-methyl-2-propanyl)-2,4,14,19-tetraoxahexacyclo[8.7.2.0.0.0.0]nonadecane-5,15,18-trione
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