Amyloid β-Protein (31-35)

Modify Date: 2024-01-10 08:08:08

Amyloid β-Protein (31-35) structure	Common Name	Amyloid β-Protein (31-35)
	CAS Number	149385-65-9	Molecular Weight	545.73600
	Density	1.137 g/cm3	Boiling Point	866.382ºC at 760 mmHg
	Molecular Formula	C₂₅H₄₇N₅O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Amyloid β-Protein (31-35)

β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.

Name	h-ile-ile-gly-leu-met-oh
Synonym	More Synonyms

Description	β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Amyloid-β Peptides Research Areas >> Neurological Disease
In Vitro	β-Amyloid (31-35) is a functional cytotoxic domain of Aβ peptide. β-Amyloid (31-35) increases the phosphorylation of biotinylated Aβ(1-40), enhances CDK-1 activity, and also inhibits binding of Aβ to cyclin B1. β-Amyloid (31-35) is cytotoxic, and such an effect can be inhibited by olomoucine in differentiated human teratocarcinoma cell line, Ntera 2/cl-D1 (NT-2) neurons[1]. β-Amyloid (31-35) shows cytotoxic effect on cerebellar granule cells (CGC). β-Amyloid (31-35) also increases caspase-3 activity in a time-dependent manner (4-24 h) at 40 μM[2].
References	[1]. Milton NG, et al. The amyloid-beta peptide binds to cyclin B1 and increases human cyclin-dependent kinase-1 activity. Neurosci Lett. 2002 Apr 5;322(2):131-3. [2]. Misiti F, et al. Fragment 31-35 of beta-amyloid peptide induces neurodegeneration in rat cerebellar granule cells via bax gene expression and caspase-3 activation. A crucial role for the redox state of methionine-35 residue. Neurochem Int. 2006 Oct;49(5):525-32.

Density	1.137 g/cm3
Boiling Point	866.382ºC at 760 mmHg
Molecular Formula	C₂₅H₄₇N₅O₆S
Molecular Weight	545.73600
Exact Mass	545.32500
PSA	205.02000
LogP	3.12420
Storage condition	−20°C

IIGLM

Isoleucinyl-isoleucinyl-glycinyl-leucinyl-methionine

amyloid B-protein fragment 31-35*acetate

ILE-ILE-GLY-LEU-MET

Amyloid β-Protein (31-35)

β-Amyloid (31-35)

Nanjing Peptide Biotech Ltd
China
Product Name: H-ILE-ILE-GLY-LEU-MET-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Zhejiang Hangyu API Co., Ltd
China
Product Name: Amyloid β-Protein (31-35)/β-Amyloid (31-35)
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

Get all suppliers and price by the below link:

Amyloid β-Protein (31-35) suppliers

Price: $70/1mg

Reference only. check more Amyloid β-Protein (31-35) price