Bromo-PEG5-phosphonic acid

Modify Date: 2023-09-07 17:28:02

Bromo-PEG5-phosphonic acid Structure
Bromo-PEG5-phosphonic acid structure
Common Name Bromo-PEG5-phosphonic acid
CAS Number 1446282-37-6 Molecular Weight 409.21
Density N/A Boiling Point N/A
Molecular Formula C12H26BrO8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG5-phosphonic acid


Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG5-phosphonic acid
Synonym More Synonyms

 Bromo-PEG5-phosphonic acid Biological Activity

Description Bromo-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H26BrO8P
Molecular Weight 409.21

 Synonyms

MFCD25424102