m-PEG5-phosphonic acid

Modify Date: 2024-01-19 14:53:08

m-PEG5-phosphonic acid Structure
m-PEG5-phosphonic acid structure
Common Name m-PEG5-phosphonic acid
CAS Number 1807512-39-5 Molecular Weight 316.29
Density N/A Boiling Point N/A
Molecular Formula C11H25O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG5-phosphonic acid


m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG5-phosphonic acid
Synonym More Synonyms

 m-PEG5-phosphonic acid Biological Activity

Description m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H25O8P
Molecular Weight 316.29

 Synonyms

MFCD28505503
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