2055016-25-4

2055016-25-4 structure

Name: m-PEG9-phosphonic acid
Chemical Name: m-PEG9-phosphonic acid
CAS Number: 2055016-25-4
Molecular Formula: C₁₉H₄₁O₁₂P
Molecular Weight: 492.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-28 23:04:53
Modify Date: 2024-01-12 14:41:58
m-PEG9-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	m-PEG9-phosphonic acid

Description	m-PEG9-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.