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1226767-94-7

1226767-94-7 structure
1226767-94-7 structure
  • Name: Bromo-PEG2-phosphonic acid diethyl ester
  • Chemical Name: Bromo-PEG2-phosphonic acid ethyl ester
  • CAS Number: 1226767-94-7
  • Molecular Formula: C10H22BrO5P
  • Molecular Weight: 333.16
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-04 17:07:33
  • Modify Date: 2024-01-14 09:49:56
  • Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG2-phosphonic acid ethyl ester
Synonyms MFCD25424121
Description Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H22BrO5P
Molecular Weight 333.16