Bromo-PEG2-phosphonic acid diethyl ester

Modify Date: 2024-01-14 09:49:56

Bromo-PEG2-phosphonic acid diethyl ester Structure
Bromo-PEG2-phosphonic acid diethyl ester structure
Common Name Bromo-PEG2-phosphonic acid diethyl ester
CAS Number 1226767-94-7 Molecular Weight 333.16
Density N/A Boiling Point N/A
Molecular Formula C10H22BrO5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-phosphonic acid diethyl ester


Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG2-phosphonic acid ethyl ester
Synonym More Synonyms

 Bromo-PEG2-phosphonic acid diethyl ester Biological Activity

Description Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H22BrO5P
Molecular Weight 333.16

 Synonyms

MFCD25424121