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500347-73-9

500347-73-9 structure
500347-73-9 structure
  • Name: PEG2-bis(phosphonic acid diethyl ester)
  • Chemical Name: PEG3-bis(phosphonic acid diethyl ester)
  • CAS Number: 500347-73-9
  • Molecular Formula: C12H28O9P2
  • Molecular Weight: 378.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-04 20:45:21
  • Modify Date: 2024-01-03 14:16:08
  • PEG2-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name PEG3-bis(phosphonic acid diethyl ester)
Synonyms MFCD26127817
Description PEG2-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H28O9P2
Molecular Weight 378.29