U-73343

Modify Date: 2024-01-02 16:55:48

U-73343 Structure
U-73343 structure
Common Name U-73343
CAS Number 142878-12-4 Molecular Weight 466.66
Density 1.2±0.1 g/cm3 Boiling Point 641.5±55.0 °C at 760 mmHg
Molecular Formula C29H42N2O3 Melting Point N/A
MSDS USA Flash Point 341.8±31.5 °C

 Use of U-73343


U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control[1].

 Names

Name 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrolidine-2,5-dione
Synonym More Synonyms

 U-73343 Biological Activity

Description U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control[1].
Related Catalog
References

[1]. Muto Y, et al. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J Pharmacol Exp Ther. 1997 Sep;282(3):1379-88.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 641.5±55.0 °C at 760 mmHg
Molecular Formula C29H42N2O3
Molecular Weight 466.66
Flash Point 341.8±31.5 °C
Exact Mass 466.319550
PSA 58.64000
LogP 5.49
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.578
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport

 Articles33

More Articles
Mechanisms of the sarcoplasmic reticulum Ca2+ release induced by P2X receptor activation in mesenteric artery myocytes.

Pharmacol. Rep. 66(3) , 363-72, (2014)

ATP is one of the principal sympathetic neurotransmitters which contracts vascular smooth muscle cells (SMCs) via activation of ionotropic P2X receptors (P2XRs). We have recently demonstrated that con...

G protein-coupled receptor signalling potentiates the osmo-mechanical activation of TRPC5 channels.

Pflugers Arch. 466(8) , 1635-46, (2014)

TRPC5 is an ion channel permeable to monovalent and divalent cations that is widely expressed in different tissues. Although implicated in the control of neurite extension and in the growth cone morph...

Brain phospholipase C/diacylglycerol lipase are involved in bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats.

Eur. J. Pharmacol. 514(2-3) , 151-8, (2005)

Bombesin receptors are mainly divided into two subtypes: BB1 receptor (neuromedin B-preferring receptor) and BB2 receptor [gastrin-releasing peptide (GRP)-preferring receptor]. Previously, we reported...

 Synonyms

2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
1-(6-{[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)-2,5-pyrrolidinedione
MFCD00211221
IN1024
1-(6-{[3-methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)pyrrolidine-2,5-dione
1-[6-({5-methoxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-14-yl}amino)hexyl]pyrrolidine-2,5-dione
1-(6-((17β-3-Methoxyestra-1,3,5(10)-triene-17-yl)amino)hexyl)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-(6-(((17β)-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-
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  • Product Name: U73343
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  • Purity: 98.0%
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Price: ¥1600/5 mg

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