157013-85-9

157013-85-9 structure

Name: U-89843A
Chemical Name: U 89843A
CAS Number: 157013-85-9
Molecular Formula: C₁₆H₂₄ClN₅
Molecular Weight: 321.85
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2022-03-27 15:51:51
Modify Date: 2025-08-22 22:27:32
U-89843A is an allosteric modulator of GABAA receptor. U-89843A enhances GABA-induced Cl- currents[1].

Name	U 89843A
Synonyms	PNU 89843 7H-Pyrrolo[2,3-d]pyrimidine, 6,7-dimethyl-2,4-di-1-pyrrolidinyl-, hydrochloride (1:1) 6,7-Dimethyl-2,4-di(pyrrolidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine hydrochloride (1:1) 6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine hydrochloride 6,7-Dimethyl-2,4-di(1-pyrrolidinyl)-7H-pyrrolo[2,3-d]pyrimidine hydrochloride (1:1)

Description	U-89843A is an allosteric modulator of GABAA receptor. U-89843A enhances GABA-induced Cl- currents[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	GABAA receptor[1]
References	[1]. Im HK, Im WB, et al. U-89843A is a novel allosteric modulator of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1995 Dec;275(3):1390-5.