LIN28 inhibitor LI71

Modify Date: 2024-01-03 17:40:20

LIN28 inhibitor LI71 structure	Common Name	LIN28 inhibitor LI71
	CAS Number	1357248-83-9	Molecular Weight	335.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₁NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LIN28 inhibitor LI71

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1].

Name	LIN28 inhibitor LI71

Description	LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1].
Related Catalog	Signaling Pathways >> Epigenetics >> MicroRNA Research Areas >> Others
Target	IC50: 7 uM (LIN28)[1]
References	[1]. Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018 Jun 5;23(10):3091-3101.

Molecular Formula	C₂₁H₂₁NO₃
Molecular Weight	335.40

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: LIN28 inhibitor LI71
Price: $900.0/100mg $1600.0/250mg $3200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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