Mal-PEG5-acid

Modify Date: 2023-01-20 14:27:18

Mal-PEG5-acid Structure
Mal-PEG5-acid structure
Common Name Mal-PEG5-acid
CAS Number 1286755-26-7 Molecular Weight 389.398
Density 1.2±0.1 g/cm3 Boiling Point 549.3±50.0 °C at 760 mmHg
Molecular Formula C17H27NO9 Melting Point N/A
MSDS N/A Flash Point 286.0±30.1 °C

 Use of Mal-PEG5-acid


Mal-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
Synonym More Synonyms

 Mal-PEG5-acid Biological Activity

Description Mal-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 549.3±50.0 °C at 760 mmHg
Molecular Formula C17H27NO9
Molecular Weight 389.398
Flash Point 286.0±30.1 °C
Exact Mass 389.168579
LogP -1.80
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.505

 Synonyms

1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
MAL-PEG5-COOH
Mal-PEG5-acid
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