1807512-46-4
1807512-46-4 structure
- Name: Mal-PEG5-PFP ester
- Chemical Name: Mal-PEG5-PFP
- CAS Number: 1807512-46-4
- Molecular Formula: C23H26F5NO9
- Molecular Weight: 555.446
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-16 03:37:32
- Modify Date: 2024-01-10 19:13:21
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Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Mal-PEG5-PFP |
|---|---|
| Synonyms |
Pentafluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester MFCD26127797 |
| Description | Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 594.2±50.0 °C at 760 mmHg |
| Molecular Formula | C23H26F5NO9 |
| Molecular Weight | 555.446 |
| Flash Point | 313.2±30.1 °C |
| Exact Mass | 555.152771 |
| LogP | 0.93 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.492 |